A drug that prevents the transmission of the HIV virus will be available in England from April, the Department of Health has confirmed.
PrEP - or pre-exposure prophylaxis - is an antiretroviral medicine which, taken once a day, stops the transmission of HIV during unprotected sex.
The pill is already available in Scotland and Wales to those at risk of contracting the virus.
It is estimated there are about 103,800 people living with HIV in the UK.
Health Secretary Matt Hancock said the roll-out of the drug in England would eliminate new HIV infections within a decade.
The cost is estimated to likely be much less than the lifetime bill for treating those who already carry the virus.
The Terrence Higgins Trust, a charity that supports those living with HIV, estimates that about 7% of the roughly 103,800 people.
Ian Green, Chief Executive at the Terrence Higgins Trust, described the development as a "game-changer" for HIV prevention.
But he said more work needed to be done to ensure the benefits of PrEP were made clear to groups other than gay and bisexual men, such as women and trans people.
Sir Elton, whose charity supports HIV prevention and treatment, welcomed the government's decision.
"Taking PrEP prevents HIV from being passed on, which is truly incredible," he told the Sunday Times.
"It is the right decision for the UK government to roll this out more widely to minimise the spread of this disease so more people are protected - which is critical in fighting any epidemic."