Elton has teamed up with the stars of It's A Sin and other campaigners in calling on the UK government to end new HIV cases by 2030.
Put together by the Elton John AIDS Foundation, Terrence Higgins Trust and National AIDS Trust, the video addresses Chancellor Rishi Sunak and Health Secretary Sajik Javid.
It starts off with the pop vocalist, who says, ''Every week 80 lives in the UK are changed forever because of HIV.''
Another participant is Olly Alexander, who comments: ''There are at least 6,600 people who are living with HIV but are not diagnosed. I urge the government: do not miss this opportunity. Fund the fight.''
The initiative comes after 35 organisations, including the EJAF, Terrence Higgins Trust, and National AIDS Trust, signed a letter to Sunak and Javid, highlighting that it's ''almost 1000 days'' since the government committed to ending the UK's HIV epidemic.
A link to the video is below: